The aadB Gene Cassette Is Associated with bla SHV Genes in Klebsiella Species Producing Extended-Spectrum β-Lactamases
نویسندگان
چکیده
منابع مشابه
The aadB gene cassette is associated with blaSHV genes in Klebsiella species producing extended-spectrum beta-lactamases.
Integrons were detected in 37 (72.5%) of 51 Klebsiella spp. producing extended-spectrum beta-lactamases by PCR with primers that targeted integrase genes and cassette regions. PCR and amplicon sequencing of the cassette regions revealed aadB and aadA2 gene cassettes that confer resistance to a range of aminoglycosides. aadB was associated with a class 1 integron on a 28-kb plasmid, pES1, that a...
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1 The Laboratory for Molecular Epidemiology and Antibiotic Research, Division of Epidemiology, Tel Aviv Sourasky Medical Center affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. 2 Clinical Microbiology Laboratory, Ha'Emek Medical Center, Afula, Israel 3 Department of Cinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel Aviv University, Tel Av...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2005
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.49.2.794-797.2005